Cellinsight, Aging, ageing- related diseases,

  T_cell                                     Image credit: Wikipedia T Cell Programming for Age Reversal:  An Overview Introduction As the global population ages, researchers are increasingly focused on understanding the biological mechanisms of aging and exploring innovative strategies for age reversal. One of the promising avenues currently being investigated is T cell programming. This approach seeks to leverage the immune system’s natural capabilities to rejuvenate cellular function, enhance regeneration, and potentially reverse age-related declines in health.  Understanding T Cells T cells are a type of lymphocyte that play a critical role in the adaptive immune response. They are essential for identifying and eliminating pathogens, coordinating immune responses, and maintaining immunological memory. T cell populations, particularly CD4+ and CD8+ T cells, undergo significant cha...

New Age reversal Technique: Gene Therapy Gene therapy                                  Image credit: Wikiped ia     Welcome to the journey into longevity science. Here genetical engineering is changing, how we fight  aging. we we'll explore age reversal and gene therapy's role in extending life and improving health.  Anti aging research and genetical engineering are merging.gene therapy lets scientists target aging causes,this could slow or reverse aging process.             We'll dive in to the age reversal science.We'll look at how cells aging,importance of biological signs, and role of DNA. We'll also see how Gene therapy has evolved,leading to today's age reversal methods.              Get ready for Longevity science ,we'll cover CRISPR, new gene delivery system,and choosing the right genes,we'll see ho...

Cellinsight Everything about human ageing and related diseases Can a chemical cocktail  reverse aging? Loss of Cellular information  is one of the most important reason for ageing. In a multicellular organism, the informations are stored in genome and epigenome, genome consist of complete information about the cell and the living organism.  Chemical-mixture    Image credit; Wikipedia Harvard genetics professor Mr. David Sinclair and his team identified a chemical cocktail,they claim this cocktail can reverse aging. The cocktail is a mixture of six or more chemicals. The chemicals includes.. Valproic acid , pramipexole , tranylcypromine ete.There findings published in AGING journal on July 12, 2023. Before we go deep in to the topic we should understand, what are stem cells. Cellular Senescence , Yemanaka factors , DNA methylation etc.  Stem cells Stem cells are the basic cells, their functionality  is not specialized,but they are able to renew th...

Old couples Image credit goes to pixabay.com Cellinsight Everything about human ageing and related diseases Cross-linking theory The cross-linking theory of aging was proposed in 1942 by Johan Bjorksten. According to this theory Collagen and other proteins undergoing structural changes due to molecular cross linkage (collagen is an important body proteins comprising 30℅ of body proteins) . In the presence of oxygen glucose molecules binding to to proteins and this cross-linked proteins causing damage to cells and tissues resulting in aging. This theory is also called as glycosylation theory of aging.  # Wrinkle and skin changes The cross-linked skin protein collagen  is responsible for wrinkles and skin changes during aging # Tendon stiffening An increased cross-linked collagen is the reason behind tendon stiffening, tendons are connective tissues which connect muscles to bones. a stiff tendon can pass more mechanical energy from muscles to bone but it lose it's elastic...

Cellinsight Everything about human ageing and related diseases Lipids Lipids are organic compounds, basically hydro carbons . They are non-polar ( means they don't have negatively or positively charged ends ) so they are not soluble in Water, but easily soluble in organic solvents such as chloroform, acetone, benzene,alcohol etc. Fats , oil , wax etc, are the examples of lipids . Lipids are necessary to make cell membranes, the outer most two layers of cell membrane is made up of phospholipids , which protect cell from surroundings and also helps cell more strong and flexible. Energy storage ( excess energy stored in adipose tissue in our body and used when ever needed ), they used to transmit nerve impulses, and many more..  Lipid metabolism Image credit goes to Commons.wikimedia.org           ( under common creative atribution)  Endocrine system in our body, releasing hormones which control growth and metabolism. According to their chemic...

Cellinsight Everything about human ageing and related diseases Immortal animals Nothing is forever in this world, death is certain, one day it will visit us. But there are some creatures that never die by natural aging process. Human cells are capable of dividing only 50 times, later the cells entered the senescence stage, and this is the exact reason for aging. Any animal which is not experiencing senescence can defeat ageing, today I am going to tell about such types of animals and how they live without the fear of ageing 1. Jelly fish (Turritopsis dohrnii)  Immortal jellyfish (Image credit goes to Wikimedia )  Jelly fishes are sea animals, included in the phylum coelenterata (cnideria). Turritopsis dohrnii is a species of jellyfish which is known as immortal jellyfish. Jellyfish reproduce both sexually and asexually.The life cycle consisted of three main stages, planulae,polyps and medusae. fertilized egg give birth to planula. The  Planula is the larval stage...