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Showing posts from 2024

Human ageing

Understanding the DNA Damage Theory of Aging: Implications for Longevity and Health

DNA Damage Theory DNA damage by UV rays Image credit: Wikipedia The DNA Damage Theory helps to understand how long we live and our health. As we age genetically our cells become more and more damaged, this can be called as cellular aging The theory shows that  Our DNA can hurt inany ways, from inside our bodies and from outside. Things like environmental factors and Oxidative stress can harm our DNA .  Key takeaways • DNA can be damage by   environmental      exposures and oxidative  stress.  • The DNA damage theory explain how    accumulated genetic damage contribute to     cellular aging and impact overall health • Understanding the mechanism of DNA damage is necessary for developing intervention to extend lifespan.  • Ongoing researches are focusing on DNA damage, cellular senescence, and age related diseases.  • DNA repair and reduce the effect of DNA damage, may promote healthy aging. Understandin...

Understanding the DNA Damage Theory of Aging: Implications for Longevity and Health

DNA Damage Theory DNA damage by UV rays Image credit: Wikipedia The DNA Damage Theory helps to understand how long we live and our health. As we age genetically our cells become more and more damaged, this can be called as cellular aging The theory shows that  Our DNA can hurt inany ways, from inside our bodies and from outside. Things like environmental factors and Oxidative stress can harm our DNA .  Key takeaways • DNA can be damage by   environmental      exposures and oxidative  stress.  • The DNA damage theory explain how    accumulated genetic damage contribute to     cellular aging and impact overall health • Understanding the mechanism of DNA damage is necessary for developing intervention to extend lifespan.  • Ongoing researches are focusing on DNA damage, cellular senescence, and age related diseases.  • DNA repair and reduce the effect of DNA damage, may promote healthy aging. Understandin...

Programmed Theory of Aging

Aging      Image credit pixabay. Com Understanding the Programmed Theory of Aging:A Comprehensive Guide The mystery of Aging has puzzled humans for centuries. While we can't stop time, scientists have explored the theories that explain why we are growing older. One of the prominent idea is The programmed theory of aging, this theory suggest that aging is n't random, instead a process controlled by our gene.  The Enigma of Aging:A Biological puzzle Aging is a complex puzzle made up of many pieces. Each piece represent biological changes,environmental factors and life choices.  As we try to fit together, we realize that aging involve both our genetics and experiences Programmed Aging:A central Theory in Gerontology Programmed aging proposes that we have a biological clock ticking down through the life. This concept grounded in genetics, implying that our cells are pre-programmed to age and die. This theory stands in contrast to wear and tear theory. Which emphasiz...

T Cell programing to reverse aging

  T_cell                                     Image credit: Wikipedia T Cell Programming for Age Reversal:  An Overview Introduction As the global population ages, researchers are increasingly focused on understanding the biological mechanisms of aging and exploring innovative strategies for age reversal. One of the promising avenues currently being investigated is T cell programming. This approach seeks to leverage the immune system’s natural capabilities to rejuvenate cellular function, enhance regeneration, and potentially reverse age-related declines in health.  Understanding T Cells T cells are a type of lymphocyte that play a critical role in the adaptive immune response. They are essential for identifying and eliminating pathogens, coordinating immune responses, and maintaining immunological memory. T cell populations, particularly CD4+ and CD8+ T cells, undergo significant cha...

Age Reversal By Gene Therapy

New Age reversal Technique: Gene Therapy Gene therapy                                  Image credit: Wikiped ia     Welcome to the journey into longevity science. Here genetical engineering is changing, how we fight  aging. we we'll explore age reversal and gene therapy's role in extending life and improving health.  Anti aging research and genetical engineering are merging.gene therapy lets scientists target aging causes,this could slow or reverse aging process.             We'll dive in to the age reversal science.We'll look at how cells aging,importance of biological signs, and role of DNA. We'll also see how Gene therapy has evolved,leading to today's age reversal methods.              Get ready for Longevity science ,we'll cover CRISPR, new gene delivery system,and choosing the right genes,we'll see ho...

Age reversal by chemical cocktail

Cellinsight Everything about human ageing and related diseases Can a chemical cocktail  reverse aging? Loss of Cellular information  is one of the most important reason for ageing. In a multicellular organism, the informations are stored in genome and epigenome, genome consist of complete information about the cell and the living organism.  Chemical-mixture    Image credit; Wikipedia Harvard genetics professor Mr. David Sinclair and his team identified a chemical cocktail,they claim this cocktail can reverse aging. The cocktail is a mixture of six or more chemicals. The chemicals includes.. Valproic acid , pramipexole , tranylcypromine ete.There findings published in AGING journal on July 12, 2023. Before we go deep in to the topic we should understand, what are stem cells. Cellular Senescence , Yemanaka factors , DNA methylation etc.  Stem cells Stem cells are the basic cells, their functionality  is not specialized,but they are able to renew th...