Genome Editing Technologies
Genome Editing: A Comprehensive Guide Genome-editing Recently Genome editing has seen remarkable advancement in the field of medicine, agriculture and biotechnology. Genome editing started in 1990s.There are many Platforms available for genetical editing, they are ZFNs (zinc finger nucleases), TALENs (transcription activator-like effector nucleases), Meganucleases, CRISPR/ Cas systems etc. Cas systems is more efficient and convenient compared to other platforms. 1.CRISPR-Cas Systems. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas systems are famous for it's simplicity and efficiency, they are widely used for Gene-editing in recent years. When a bacterium infected by bacteriophage- virus, bacterial immune system, that's Crispr-Cas systems protect them. Crispr-Cas9 system found in streptococcus pyogenes , when virus attack this bacteria the Cas9- system detect it and bacteria produced a guide RNA ( gRNA ) that's complementary to viral DNA , i...