DNA Damage Theory DNA damage by UV rays Image credit: Wikipedia The DNA Damage Theory helps to understand how long we live and our health. As we age genetically our cells become more and more damaged, this can be called as cellular aging The theory shows that Our DNA can hurt inany ways, from inside our bodies and from outside. Things like environmental factors and Oxidative stress can harm our DNA . Key takeaways • DNA can be damage by environmental exposures and oxidative stress. • The DNA damage theory explain how accumulated genetic damage contribute to cellular aging and impact overall health • Understanding the mechanism of DNA damage is necessary for developing intervention to extend lifespan. • Ongoing researches are focusing on DNA damage, cellular senescence, and age related diseases. • DNA repair and reduce the effect of DNA damage, may promote healthy aging. Understandin...
Cellinsight Everything about human ageing and related diseases Can a chemical cocktail reverse aging? Loss of Cellular information is one of the most important reason for ageing. In a multicellular organism, the informations are stored in genome and epigenome, genome consist of complete information about the cell and the living organism. Chemical-mixture Image credit; Wikipedia Harvard genetics professor Mr. David Sinclair and his team identified a chemical cocktail,they claim this cocktail can reverse aging. The cocktail is a mixture of six or more chemicals. The chemicals includes.. Valproic acid , pramipexole , tranylcypromine ete.There findings published in AGING journal on July 12, 2023. Before we go deep in to the topic we should understand, what are stem cells. Cellular Senescence , Yemanaka factors , DNA methylation etc. Stem cells Stem cells are the basic cells, their functionality is not specialized,but they are able to renew th...