Cellinsight, Aging, ageing- related diseases,

Everything about human ageing and related  diseases Human Life cycle Image credit: Pixabay   Aging is universal phenomenon, seen in all living organisms. Evolutionary senescent theory , helps to understand Aging mechanism deeply and provide a deep insight into the survival strategies of different animal species. This theory is focusing on how natural selection affects Aging , and longevity . The theory teach us the complex interaction between environment, gens, and body functions. Key takeaway # T his theory give us a deep insight into the complex interplay between, physiological  genetical and environmental factors that shapes Aging mechanism of living Organisms.  # Evolutionary senescent theory,tells you how natural selection influence Aging and life span.  #This theory help us to understand the evolution of life and longevity.  Evolutionary Senescent Theory: An Introduction This theory unravel the mysteries of Aging and senescence . The researches, ...

DNA Damage Theory DNA damage by UV rays Image credit: Wikipedia  DNA Damage Theory helps to understand how long we live and our health. As we age genetically our cells become more and more damaged, this can be called as cellular aging The theory shows that  Our DNA can hurt inany ways, fr The om inside our bodies and from outside. Things like environmental factors and Oxidative stress can harm our DNA .  Key takeaways • DNA can be damage by   environmental      exposures and oxidative  stress.  • The DNA damage theory explain how    accumulated genetic damage contribute to     cellular aging and impact overall health • Understanding the mechanism of DNA damage is necessary for developing intervention to extend lifespan.  • Ongoing researches are focusing on DNA damage, cellular senescence, and age related diseases.  • DNA repair and reduce the effect of DNA damage, may promote healthy aging. Under...

Aging      Image credit pixabay. Com Understanding the Programmed Theory of Aging:A Comprehensive Guide The mystery of Aging has puzzled humans for centuries. While we can't stop time, scientists have explored the theories that explain why we are growing older. One of the prominent idea is The programmed theory of aging, this theory suggest that aging is n't random, instead a process controlled by our gene.  The Enigma of Aging:A Biological puzzle Aging is a complex puzzle made up of many pieces. Each piece represent biological changes,environmental factors and life choices.  As we try to fit together, we realize that aging involve both our genetics and experiences Programmed Aging:A central Theory in Gerontology Programmed aging proposes that we have a biological clock ticking down through the life. This concept grounded in genetics, implying that our cells are pre-programmed to age and die. This theory stands in contrast to wear and tear theory. Which emphasiz...

  T_cell                                                                 Image credit: Wikipedia T Cell Programming for Age Reversal:  An Overview Introduction As the global population ages, researchers are increasingly focused on understanding the biological mechanisms of aging and exploring innovative strategies for age reversal. One of the promising avenues currently being investigated is T cell programming. This approach seeks to leverage the immune system’s natural capabilities to rejuvenate cellular function, enhance regeneration, and potentially reverse age-related declines in health.  Understanding T Cells T cells are a type of lymphocyte that play a critical role in the adaptive immune response. They are essential for identifying and eliminating pathogens, coordinating immune responses, and maintaining imm...

New Age reversal Technique: Gene Therapy Gene therapy                                  Image credit: Wikiped ia     Welcome to the journey into longevity science. Here genetical engineering is changing, how we fight  aging. we we'll explore age reversal and gene therapy's role in extending life and improving health.  Anti aging research and genetical engineering are merging.gene therapy lets scientists target aging causes,this could slow or reverse aging process.             We'll dive in to the age reversal science.We'll look at how cells aging,importance of biological signs, and role of DNA. We'll also see how Gene therapy has evolved,leading to today's age reversal methods.              Get ready for Longevity science ,we'll cover CRISPR, new gene delivery system,and choosing the right genes,we'll see ho...

 Cellinsight Everything about human ageing and related diseases Can a chemical cocktail  reverse aging? Loss of Cellular information   is one of the most important reason for  ageing . In a multicellular organism, the informations are stored in  genome  and  epigenome , genome consist of complete information about the cell and the living organism.  Age-reversal-chemical-technique     Harvard genetics professor  Mr. David Sinclair  and his team identified a chemical cocktail,they claim this cocktail can reverse aging. The cocktail is a mixture of six or more chemicals. The chemicals includes..  Valproic   acid ,  pramipexole ,  tranylcypromine  ete.There findings published in AGING journal on July 12, 2023. Before we go deep in to the topic we should understand, what are stem cells.  Cellular   Senescence ,  Yemanaka   factors ,  DNA   methylation  etc.  Stem cells...

Old couples Image credit goes to pixabay.com Cellinsight Everything about human ageing and related diseases Cross-linking theory The cross-linking theory of aging was proposed in 1942 by Johan Bjorksten. According to this theory Collagen and other proteins undergoing structural changes due to molecular cross linkage (collagen is an important body proteins comprising 30℅ of body proteins) . In the presence of oxygen glucose molecules binding to to proteins and this cross-linked proteins causing damage to cells and tissues resulting in aging. This theory is also called as glycosylation theory of aging.  # Wrinkle and skin changes The cross-linked skin protein collagen  is responsible for wrinkles and skin changes during aging # Tendon stiffening An increased cross-linked collagen is the reason behind tendon stiffening, tendons are connective tissues which connect muscles to bones. a stiff tendon can pass more mechanical energy from muscles to bone but it lose it's elastic...